Population
Isolated specimens of right atrial appendage from 138 subjects with atrial disease or dysfunction and from 7…
Comparison
Electrophysiological examination using… vs Specimens from 7 subjects with clinically normal…
Design
Preclinical
Authors
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May alter atrial excitability in disease; leaves open whether potassium modulation can normalize potentials in human AF models.
Diseased human atrial cells exhibit significant hypopolarization and altered potassium conductance, which may fundamentally impact their electrical and mechanical activity.
Eick et al. (1979) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: