What does this research mean for the field?

The HemoScreen point-of-care hematology analyzer demonstrates strong analytical and diagnostic performance for five-part white blood cell differentials in pediatric venous samples. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the analytical accuracy, diagnostic concordance, and abnormal-cell flagging performance of the HemoScreen point-of-care hematology analyzer for five-part white blood cell differentials in pediatric inpatients.

August 22, 2026International Journal of Laboratory Hematology

Point‐of‐Care White Blood Cell Differential Testing in Pediatric Inpatients (2 Months–17 Years): How Does HemoScreen Perform?

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To evaluate the analytical accuracy, diagnostic concordance, and abnormal-cell flagging performance of the HemoScreen point-of-care hematology analyzer for five-part white blood cell differentials in pediatric inpatients.
Tested venous EDTA blood samples from pediatric inpatients aged 2 months to 17 years (N=138 suitable for analysis).
Compared HemoScreen differential percentages directly to cytologist-reviewed digital blood smears (CellaVision DC-1) and absolute counts to a Sysmex XN-1000 composite reference.
Correlations across white blood cell subsets were strong to excellent (ρ = 0.625–0.977), with mean bias within or near EFLM acceptable limits for neutrophils and lymphocytes.
Diagnostic agreement was excellent for neutropenia, neutrophilia, and lymphocytopenia, and good for lymphocytosis, monocytosis, and eosinophilia.
HemoScreen flagged 31.9% of samples for abnormal cells, showing 74.1% sensitivity, 78.4% specificity, 45.5% positive predictive value, 92.6% negative predictive value, and 77.5% overall efficiency.

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Implication

Diagnostic evaluation demonstrates accurate five-part white blood cell differentials in pediatric inpatients, indicating point-of-care utility for rapid bedside clinical assessment.

Cite This Study

Correani et al. (2026) studied this question.

synapsesocial.com/papers/6a895f62ca7ade938187e0d2 https://doi.org/10.1111/ijlh.70228

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Implication

Diagnostic evaluation demonstrates accurate five-part white blood cell differentials in pediatric inpatients, indicating point-of-care utility for rapid bedside clinical assessment.

Point‐of‐Care White Blood Cell Differential Testing in Pediatric Inpatients (2 Months–17 Years): How Does HemoScreen Perform?

Key Points

Discussion

Implication

Cite This Study

Point‐of‐Care White Blood Cell Differential Testing in Pediatric Inpatients (2 Months–17 Years): How Does HemoScreen Perform?

Key Points

Discussion

Implication

Cite This Study

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