BuDrL sHMIEDICAL JOURNAL tance of acute haemorrhagic pancreatitis with two com- mon acute abdominal conditions are noted.The serum amylase and lipase levels were measured in 25 normal subjects and in 12 patients with past or present pancreatic disease.No significant serum enzyme response was obtained after pancreatic stimulation with morphine, methacholine, secretin, or pancreozymin in any of the individuals investigated, and the suggestion that the response obtained with these substances may be of value as an indication of the presence of pancreatitis was not confirmed.The serum amylase and lipase levels were investigated in three cases of acute haemorrhagic pancreatitis and in certain other acute abdominal conditions; the highest readings were obtained in acute pancreatitis, but a two- fold or threefold increase was found to be fairly com- mon in cases of perforated duodenal and juxtapyloric ulcers, and high levels were recorded in patients with calculi in the common bile duct.The excretion of urinary diastase during the first twenty-four hours in hospital was measured in three cases of acute pancreatitis and in 41 other patients with acute abdominal disease: wide variations were recorded, and this investigation is not considered useful or reliable.
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Oliver Garrod (1955) studied this question.