Why the study?
Does the presence of single or combined prothrombotic risk factors increase the risk of recurrent VTE in pediatric patients after a first spontaneous VTE?
Population
301 pediatric patients with an objectively confirmed first episode of spontaneous venous thromboembolism
Comparison
Presence of single or combined prothrombotic… vs Absence of prothrombotic risk factors
Design
Cohort
Follow-up
median 7 years (range, 6 months to 15 years)
Authors
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May support risk stratification after pediatric VTE; leaves open whether genetic screening improves outcomes.
Does the presence of single or combined prothrombotic risk factors increase the risk of recurrent VTE in pediatric patients after a first spontaneous VTE?
The presence of combined prothrombotic defects dramatically increases the risk of recurrent VTE in children, suggesting a need for genetic screening in pediatric VTE patients.
Ulrike Nowak‐Göttl (2001) studied this question.
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