Key result
Obesity significantly increased the risk of incident hypertension in adults with prehypertension, with adjusted hazard ratios ranging from 1.29 to 1.34 across different anthropometric indices.
Why the study?
This study aimed to investigate the impact of anthropometric indices of obesity on the incidence of hypertension in adults with prehypertension.
Does obesity, as measured by various anthropometric indices, increase the risk of incident hypertension in adults with prehypertension?
Cohort (n=1,838)
Yes
Does obesity, as measured by various anthropometric indices, increase the risk of incident hypertension in adults with prehypertension?
Hazard Ratio: 1.33 (95% CI 1.18–1.5)
Absolute Event Rate: 83.1% vs 65.81%
p-value: p=<0.001
In adults with prehypertension, obesity defined by BMI, waist circumference, waist-hip ratio, or body fat percentage significantly increases the long-term risk of developing overt hypertension.
Obesity indices were associated with higher hypertension incidence in prehypertension; leaves open whether targeting them alters progression.
PURPOSE: This study aimed to investigate the impact of anthropometric indices of obesity (body mass index [BMI], waist circumference, waist hip ratio, and body fat percentage) on the incidence of hypertension in adults with prehypertension. METHODS: A longitudinal study design using secondary data form the Korean Genome and Epidemiology Study was employed. The study included 1,838 adults with prehypertension tracked every two years from 2001 to 2018. Statistical analyses, including frequency assessments, number of cases per 1,000 person-years, log-rank tests, Kaplan-Meier curves, and Cox's proportional hazards regression, were conducted using SPSS version 25. RESULTS: Over the observation period (15,783.6 person-years), 1,136 individuals developed hypertension. The incidence of hypertension was significantly higher in the obesity groups defined by BMI (hazard ratio [HR] = 1.33), waist circumference (HR = 1.34), waist hip ratio (HR = 1.29), and body fat percentage (HR = 1.31) compared to the non-obese group. These findings indicate an increased risk of hypertension associated with obesity as measured by these indices. CONCLUSION: The study underscores the importance of avoiding obesity to prevent hypertension in individuals with prehypertension. Specifically, BMI, waist circumference, waist hip circumference, and body fat percentage were identified as significant risk factors for hypertension. The results suggest the need for individualized weight control interventions, emphasizing the role of health professionals in addressing the heightened hypertension risk in this population.
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Jang et al. (2024) conducted a cohort in Prehypertension (n=1,838). Obesity (measured by BMI, waist circumference, waist-hip ratio, and body fat percentage) vs. Non-obese group was evaluated on Incidence of hypertension (HR 1.33, 95% CI 1.18-1.50, p=<0.001). Obesity significantly increased the risk of incident hypertension in adults with prehypertension, with adjusted hazard ratios ranging from 1.29 to 1.34 across different anthropometric indices.
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