Key result
The negative correlation between central obesity (waist circumference) and aortic pressure augmentation was significantly attenuated in women compared to men (interaction P=0.045).
Why the study?
Obesity is negatively associated with pressure wave reflection, but obesity-dependent dilation of muscular arteries is attenuated in women compared with men, prompting investigation of sex differences in this relationship.
Is the inverse association between obesity and aortic pressure augmentation attenuated in women compared to men?
Population
928 adults (mean age, 56 ± 10 years) from a general population cohort
Comparison
Obesity indices (BMI and waist circumference) stratified by sex
Design
Cross-sectional study
Authors
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Sex differences in obesity-related wave reflection merit cautious interpretation in risk models; leaves open links to outcomes in prospective data.
Cross-Sectional (n=928)
Is the inverse association between obesity and aortic pressure augmentation attenuated in women compared to men?
p-value: p=0.045
The inverse relationship between central obesity and aortic pressure augmentation is attenuated in women compared to men.
Tagawa et al. (2024) conducted a cross-sectional in General population (n=928). Obesity (BMI and waist circumference) vs. Lower BMI/waist circumference was evaluated on Aortic augmentation index (p=0.045). The negative correlation between central obesity (waist circumference) and aortic pressure augmentation was significantly attenuated in women compared to men (interaction P=0.045).
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