Key result
Decreased eGFR was correlated with peripheral artery occlusive disease (ABI <0.9, p=0.049) and increased arterial stiffness in patients with stage 3-5 chronic kidney disease.
Why the study?
What are the determinants of peripheral artery occlusive disease and arterial stiffness in patients with stage 3-5 chronic kidney disease?
Population
169 patients with stage 3-5 chronic kidney disease (CKD) in one regional hospital in southern Taiwan.
Design
Cross-sectional
Authors
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Supports vascular screening in advanced CKD; hypothesis-generating for eGFR decline driving stiffness.
Cross-Sectional (n=169)
No
What are the determinants of peripheral artery occlusive disease and arterial stiffness in patients with stage 3-5 chronic kidney disease?
p-value: p=0.049
In patients with stage 3-5 CKD, decreased eGFR and traditional atherosclerotic risk factors like diabetes are significantly correlated with peripheral artery occlusive disease and increased arterial stiffness.
Chen et al. (2009) conducted a cross-sectional in Chronic Kidney Disease (n=169). Decreased estimated glomerular filtration rate (eGFR) and diabetes mellitus was evaluated on Peripheral artery occlusive disease (ABI <0.9) and arterial stiffness (brachial-ankle pulse wave velocity) (p=0.049). Decreased eGFR was correlated with peripheral artery occlusive disease (ABI <0.9, p=0.049) and increased arterial stiffness in patients with stage 3-5 chronic kidney disease.
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