Key result
Receipt of a CRT-D device in heart failure patients was associated with significant improvements in heart rate variability parameters and clinical status over 1 year (P<0.001).
Why the study?
Does cardiac resynchronization therapy with defibrillator improve heart rate variability and clinical status in patients with heart failure?
Observational (n=1,421)
Does cardiac resynchronization therapy with defibrillator improve heart rate variability and clinical status in patients with heart failure?
p-value: p=<0.001
CRT-D implantation is associated with significant improvements in device-measured heart rate variability, quality of life, and functional status over 1 year in heart failure patients.
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May support CRT-D monitoring of HRV in HF; hypothesis-generating and requires RCTs before practice change.
Gilliam et al. (2007) conducted an observational in Heart failure (n=1,421). Cardiac resynchronization therapy with defibrillator (CRT-D) was evaluated on Changes in HRV (SDANN and HRV footprint) and clinical status over time (p=<0.001). Receipt of a CRT-D device in heart failure patients was associated with significant improvements in heart rate variability parameters and clinical status over 1 year (P<0.001).
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