Key result
Nonalcoholic fatty liver disease was a strong predictor of coronary atherosclerosis (OR 2; P<0.04) and was associated with a higher prevalence of calcified coronary plaques (67% vs 34%; P<0.001).
Why the study?
Is nonalcoholic fatty liver disease associated with an increased presence of coronary plaques in patients with low to intermediate risk for CAD?
Population
61 subjects with low to intermediate risk for CAD, including 29 with nonalcoholic fatty liver disease and 32…
Comparison
Nonalcoholic fatty liver disease (NAFLD) vs No NAFLD (sex- and age-matched controls)
Design
Case-control
Authors
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NAFLD may aid CAD risk stratification in low-intermediate risk patients; leaves open whether assessment improves outcomes.
Case-Control (n=61)
Is nonalcoholic fatty liver disease associated with an increased presence of coronary plaques in patients with low to intermediate risk for CAD?
Odds Ratio: 2
p-value: p=<.04
NAFLD is an independent predictor of coronary atherosclerosis, suggesting its assessment may improve cardiovascular risk stratification even in the absence of metabolic syndrome.
Assy et al. (2010) conducted a case-control in Nonalcoholic fatty liver disease (n=61). Nonalcoholic fatty liver disease vs. Without NAFLD was evaluated on Coronary atherosclerosis (OR 2, p=<.04). Nonalcoholic fatty liver disease was a strong predictor of coronary atherosclerosis (OR 2; P<0.04) and was associated with a higher prevalence of calcified coronary plaques (67% vs 34%; P<0.001).
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