Why the study?
NAFLD is suggested to confer cardiovascular risk and may initiate CAD, but its association with CAD, high-risk plaque features, and stenosis severity required evaluation.
Is non-alcoholic fatty liver disease (NAFLD) associated with the presence and severity of coronary artery disease and high-risk plaque features on computed tomography?
Population
800 patients with suspected obstructive CAD planned for CCTA
Comparison
Patients with CAD vs patients without CAD, and NAFLD presence
Design
Cross-sectional study
Authors
Loading...
NAFLD may identify high-risk CAD on CCTA; leaves open causality and need for prospective outcome trials.
Is non-alcoholic fatty liver disease (NAFLD) associated with the presence and severity of coronary artery disease and high-risk plaque features on computed tomography?
NAFLD is strongly associated with the presence of CAD, higher grades of coronary stenosis, and high-risk plaque features on CCTA, suggesting it constitutes an independent cardiovascular risk factor.
Saraya et al. (2021) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: