Key result
Concurrent training with blood flow restriction showed a pro-inflammatory profile after 12 weeks, with significant increases in C-reactive protein (p=0.049) and interleukin-6 (p=0.016).
Why the study?
Does concurrent training with blood flow restriction reduce inflammatory markers in healthy older adults compared to concurrent training alone?
Does concurrent training with blood flow restriction reduce inflammatory markers in healthy older adults compared to concurrent training alone?
p-value: p=0.049
Concurrent training with blood flow restriction in older adults induces a pro-inflammatory profile compared to concurrent training alone over 12 weeks.
Concurrent training with blood flow restriction was associated with pro-inflammatory changes in older adults; hypothesis-generating and requires confirmation in randomized trials.
The aging process is associated with several changes in the elderly such as the decrease in cardiorespiratory fitness, strength and muscle mass, in addition to chronic low-grade inflammation. Concurrent training with blood flow restriction can be an interesting alternative to improve functional capacity with low mechanical stress in the elderly. The purpose of this study was to compare the inflammatory effects in older individuals submitted to two different protocols of concurrent training. Twenty-two healthy older adults (63.7±3.8 years; 69.8±8.9 kg; 1.6±0.1 m) performed 12 weeks of concurrent training (CT) or concurrent training with blood flow restriction (CTBFR) and the effects on inflammatory markers were analyzed. We found inflammatory behavior for the CTBFR group with a significant difference in serum concentration of C-reactive protein between pre- and post-moment (0.96±0.37 to 1.71±1.45, p=0.049), with no difference between groups, and a time effect in interleukin-6 (pre=0.86±0.43; post=1.02±0.46, p=0.016). We conclude that the CTBFR showed a pro-inflammatory profile after the period of intervention whereas the CT showed the opposite.
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Souza et al. (2017) studied healthy older adults (n=22). Concurrent training with blood flow restriction (CTBFR) vs. Concurrent training (CT) was evaluated on inflammatory markers (C-reactive protein and interleukin-6) (p=0.049). Concurrent training with blood flow restriction showed a pro-inflammatory profile after 12 weeks, with significant increases in C-reactive protein (p=0.049) and interleukin-6 (p=0.016).
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