Effect of Sub Lethal Dose of Pyrethroids Insecticide on Hepatocyte of Female Albino Mice

Agricultural pesticides play an important and pivotal role in agricultural production processes in all their stages, and the superior success shown by agricultural pesticides in controlling agricultural pests has led to greater dependence on them. Pesticides accumulate in the food chain and the human environment over time in both cases, including the overuse or misuse of many of them in various fields at times. However, they are also used to treat agricultural biting and sucking insects. The current paper aims to investigate the effect of a sub lethal dose of pyrethiored insecticide on the hepatocytes of male albino mice. Based on the current results, the hepatocyte structure and tissues section clarify the effect of Permethrin insecticide, including changes such as necrosis, venous hypertrophy, and increased vacuoles. The hepatic portal and vacuoles show vacuolar degeneration, which means that the changes are severe and an indication of the toxicity of insecticide, and this difference appears to be significant compared to the control.