Key result
In US adults with isolated systolic hypertension, low diastolic blood pressure (<70 mmHg) was associated with an almost two-fold higher prevalence of diabetes and cardiovascular disease.
Why the study?
Does low DBP (< 70 mmHg) associate with a higher prevalence of cardiovascular disease compared to higher DBP (70-89 mmHg) in adults with isolated systolic hypertension?
Population
19,808 adult hypertensives from the US National Health Nutrition Examination Survey 1999-2006, specifically…
Comparison
Low diastolic blood pressure (DBP < 70 mmHg) vs Higher diastolic blood pressure (DBP 70-89 mmHg)
Design
Cross-sectional
Authors
Loading...
Should not alter DBP targets in isolated systolic hypertension; leaves open whether low DBP marks higher-risk patients or reflects confounding.
Cross-Sectional (n=19,808)
Yes
Does low DBP (< 70 mmHg) associate with a higher prevalence of cardiovascular disease compared to higher DBP (70-89 mmHg) in adults with isolated systolic hypertension?
p-value: p=<0.01
In US adults with isolated systolic hypertension, a low diastolic blood pressure (<70 mmHg) is associated with a significantly higher prevalence of cardiovascular disease and diabetes.
Franklin et al. (2011) conducted a cross-sectional in Isolated systolic hypertension (n=19,808). Low diastolic blood pressure (< 70 mmHg) vs. Higher diastolic blood pressure (≥ 70-89 mmHg) was evaluated on Prevalence of diabetes and cardiovascular disease (p=<0.01). In US adults with isolated systolic hypertension, low diastolic blood pressure (<70 mmHg) was associated with an almost two-fold higher prevalence of diabetes and cardiovascular disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: