Key result
A higher cardiovascular health index score was significantly associated with lower common carotid intima-media thickness, with each unit increase in CVHI score corresponding to a 5.54 μm decrease in CIMT.
Why the study?
The utility of the cardiovascular health index in under-studied populations in sub-Saharan Africa was unclear, prompting evaluation of its association with common carotid intima-media thickness.
Is the cardiovascular health index associated with subclinical atherosclerosis (measured by CIMT) in apparently healthy sub-Saharan African populations?
Population
9011 participants from Burkina Faso, Ghana, Kenya, and South Africa
Comparison
Cardiovascular health index score levels
Design
Cross-sectional study
Authors
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Supports CVHI as marker of subclinical atherosclerosis in sub-Saharan Africans; extends prior associations but remains hypothesis-generating and should not yet change practice.
Cross-Sectional (n=9,011)
Yes
Is the cardiovascular health index associated with subclinical atherosclerosis (measured by CIMT) in apparently healthy sub-Saharan African populations?
Mean Difference: -5.54 (95% CI -6.75–-4.32)
p-value: p=<0.001
The cardiovascular health index is a strong marker of subclinical atherosclerosis in sub-Saharan African populations, supporting its utility as a simple screening tool for primary prevention.
Nonterah et al. (2021) conducted a cross-sectional in Subclinical atherosclerosis (n=9,011). Cardiovascular health index (CVHI) vs. Lower CVHI scores was evaluated on Common carotid intima-media thickness (CIMT) (β -5.54, 95% CI -6.75, -4.32, p=<0.001). A higher cardiovascular health index score was significantly associated with lower common carotid intima-media thickness, with each unit increase in CVHI score corresponding to a 5.54 μm decrease in CIMT.
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