Why the study?
Does diabetic autonomic neuropathy impair the glucagon response to hypoglycemia?
Population
Diabetics with autonomic neuropathy (N=9), diabetics without neuropathy (N=8), and normal subjects (N=9).
Comparison
Insulin-induced hypoglycemia and arginine… vs Normal subjects and diabetics without neuropathy
Design
Cross-sectional
Authors
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Neuropathic diabetes was associated with absent glucagon response to hypoglycemia; hypothesis-generating for contribution to metabolic instability.
Does diabetic autonomic neuropathy impair the glucagon response to hypoglycemia?
Diabetic autonomic neuropathy is associated with a loss of glucagon response to hypoglycemia, which may contribute to metabolic instability.
Maker et al. (1977) studied this question.
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