Key result
Autopsy of an 80-year-old female who died after a syncopal episode revealed a giant intrapericardial lipoma (820 g) causing acute myocardial necrosis, likely due to coronary artery compression.
Why the study?
Lipomas are rarely found in the pericardial cavity, yet despite being histopathologically benign, their rapid growth can lead to life-threatening complications.
Case Report (n=1)
Giant intrapericardial lipomas, though histopathologically benign, can cause life-threatening complications such as acute myocardial necrosis and sudden cardiac death due to coronary compression.
Alerts clinicians to rare fatal coronary compression by giant lipomas; case report leaves open detection and management questions.
Introduction. Even though lipomas are the most common benign tumors, they are rarely found in the pericardial cavity. Although histopathologically benign, they can cause life-threatening complications by rapid growth and may there-fore be clinically considered malignant. Case report. We present an 80-year-old female who was injured during a syncopal episode when falling from a standing height and suffered bodily injuries for which she was hospitalized. In the further course of her short-term hospital treatment, death occurred, and the cause of death was marked as ?un-known?. At the autopsy, a dilated and tense pericardium filling up a large part of the chest cavity was noted. A well-encapsulated soft tissue mass, 2 0 ? 1 8 ? 3 cm in size, weighing 820 g, was visualized in the pericardial cavity. Histopathological examination revealed that the mass was a lipoma and showed acute myocardial necrosis; therefore, it was assumed that the cause of death was probably due to the compression of lipoma on coronary arteries. Conclusion. Even though intrapericardial lipomas are benign tumors, they can cause life-threatening complications and sudden cardiac death. There are numerous diagnostic methods capable of detecting intrapericardial lipomas, and with timely treatment, the patient can be cured.
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Bogdanović et al. (2022) conducted a case report in Giant intrapericardial lipoma (n=1). Giant intrapericardial lipoma was evaluated on Autopsy findings. Autopsy of an 80-year-old female who died after a syncopal episode revealed a giant intrapericardial lipoma (820 g) causing acute myocardial necrosis, likely due to coronary artery compression.
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