What question did this study set out to answer?

To determine the prevalence of symptomatic and silent myocardial ischaemia in patients presenting with left ventricular hypertrophy secondary to essential hypertension.

May 1, 1992HeartOpen Access

Symptomatic and silent myocardial ischaemia in hypertensive patients with left ventricular hypertrophy.

View Full Paper

Ask AI

Bookmark

Why the study?

What is the prevalence of symptomatic and silent myocardial ischaemia in patients with hypertensive left ventricular hypertrophy?

Population

90 patients with left ventricular hypertrophy due to essential hypertension.

Design

Cross-sectional

Authors

SPStuart D. PringleQueen's University Belfast FDF G DunnGeneral Cardiology ATA.C. TweddelHull and East Yorkshire Hospitals NHS Trust

Discussion

Member takes

Implication

Silent ischemia is common in hypertensive LVH even without obstructive CAD; leaves open whether detection improves outcomes.

Key Points

To determine the prevalence of symptomatic and silent myocardial ischaemia in patients presenting with left ventricular hypertrophy secondary to essential hypertension.
Cross-sectional evaluation of 90 patients (68 men, 22 women; mean age 57 years, range 25–79) with hypertensive left ventricular hypertrophy at a university medical cardiology department.
Diagnostic assessments included 48-hour ambulatory ST-segment monitoring (N=90), exercise electrocardiography (n=79), stress thallium scintigraphy (n=80), and coronary arteriography (n=35).
Ambulatory electrocardiographic monitoring identified ST-segment depression in 43 of 90 patients, with a median of 16 episodes (range 1–84) and a median duration of 8.6 minutes (range 2–17), exceeding 90% silent episodes.
Stress testing revealed positive exercise electrocardiograms in 26 of 79 patients and reversible thallium perfusion defects in 48 of 80 patients, despite only 5 experiencing exercise-induced chest pain.
Coronary arteriography confirmed significant coronary artery disease in 18 of 35 evaluated patients, 7 of whom reported no history of chest pain.

Structured PICO

What is the prevalence of symptomatic and silent myocardial ischaemia in patients with hypertensive left ventricular hypertrophy?

Population

90 patients (68 men and 22 women; mean age 57, range 25 to 79) with left ventricular hypertrophy due to essential hypertension.

Intervention

Diagnostic evaluation including 48 hour ambulatory ST segment monitoring, exercise electrocardiography, stress thallium scintigraphy, and coronary arteriography

Outcome

Prevalence of symptomatic and silent myocardial ischaemiasurrogate

Silent myocardial ischemia is highly prevalent in patients with hypertensive left ventricular hypertrophy, occurring frequently even in the absence of epicardial coronary artery disease.

Cite This Study

Pringle et al. (1992) studied this question.

synapsesocial.com/papers/6a89765441f4089922bd5ee4 https://doi.org/10.1136/hrt.67.5.377

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Symptomatic and silent myocardial ischaemia in hypertensive patients with left ventricular hypertrophy.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Symptomatic and silent myocardial ischaemia in hypertensive patients with left ventricular hypertrophy.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider