Key result
Cardiogoniometry yielded a higher diagnostic accuracy (83%) and sensitivity (70%) than electrocardiography (63% and 35%, respectively) for detecting myocardial ischaemia or lesions on CMRI.
Why the study?
Does cardiogoniometry improve the detection of myocardial ischaemia and/or lesions compared to resting electrocardiography in patients with suspected or known stable coronary artery disease?
Cross-Sectional (n=40)
Single-blind
Does cardiogoniometry improve the detection of myocardial ischaemia and/or lesions compared to resting electrocardiography in patients with suspected or known stable coronary artery disease?
Absolute Event Rate: 83% vs 63%
Cardiogoniometry demonstrated higher diagnostic accuracy and sensitivity than standard resting ECG for detecting myocardial ischemia or structural lesions when compared to cardiac MRI.
Supports cardiogoniometry as a promising ECG alternative for ischemia detection; hypothesis-generating and requires prospective confirmation before clinical adoption.
AIMS: Cardiogoniometry (CGM) is a spatio-temporal five-lead resting electrocardiographic method utilizing automated analysis. The purpose of this study was to determine CGM's and electrocardiography (ECG)'s accuracy for detecting myocardial ischaemia and/or lesions in comparison with perfusion cardiac magnetic resonance imaging (CMRI) and late gadolinium enhancement (LGE). METHODS AND RESULTS: Forty (n= 40) patients with suspected or known stable coronary artery disease were examined by CGM and resting ECG directly prior to CMRI including adenosine stress perfusion (ASP) and LGE. The investigators visually reading the CMRI were blinded to the CGM and ECG results. Half of the patients (n= 20) had a normal CMRI while the other half presented with either abnormal ASP and/or detectable LGE. Cardiogoniometry yielded an accuracy of 83% (sensitivity 70%) and ECG of 63% (sensitivity 35%) compared with CMRI. CONCLUSIONS: In this pilot study CGM compares more favourably than ECG with the detection of ischaemia and/or structural myocardial lesions on CMRI.
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Birkemeyer et al. (2012) conducted a cross-sectional in suspected or known stable coronary artery disease (n=40). Cardiogoniometry (CGM) vs. Electrocardiography (ECG) was evaluated on accuracy for detecting myocardial ischaemia and/or lesions compared with CMRI. Cardiogoniometry yielded a higher diagnostic accuracy (83%) and sensitivity (70%) than electrocardiography (63% and 35%, respectively) for detecting myocardial ischaemia or lesions on CMRI.
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