Why the study?
Does complete intrapericardial denervation alter the cardiovascular, renal, and endocrine responses to head-out water immersion in rhesus monkeys?
Does complete intrapericardial denervation alter the cardiovascular, renal, and endocrine responses to head-out water immersion in rhesus monkeys?
Complete cardiac denervation does not prevent the natriuresis or rise in ANP associated with head-out water immersion in rhesus monkeys, suggesting extracardiac sensing mechanisms mediate these responses.
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Cardiac denervation fails to block ANP release or natriuresis during immersion in monkeys; leaves open extracardiac volume-sensing mechanisms and requires human validation.
McKeever et al. (1995) studied this question.
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