February 1, 1962Acta Physiologica Scandinavica

The Effect of Lowering the Pulse Pressure in the Carotid Arteries on the Cardiac Output in the Cat

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Why the study?

Does lowering carotid pulse pressure affect cardiac output in anaesthetized cats?

Population

Anaesthetized, spontaneously breathing cats (n=10)

Comparison

Partial occlusion of a screw-clamp around the… vs Normal carotid pressure

Design

Preclinical

Authors

AGA. C. GroomUniversity of London BLBirger LöfvingUniversity of Gothenburg SRSam RowlandsBournemouth University

Discussion

Member takes

Implication

No support for CO augmentation via carotid pulse pressure reduction in cats; leaves open translation to human baroreflex physiology.

Structured PICO

Does lowering carotid pulse pressure affect cardiac output in anaesthetized cats?

Population

Anaesthetized, spontaneously breathing cats (n=10)

Intervention

Partial occlusion of a screw-clamp around the innominate artery to reduce carotid pulse pressure

Comparator

Normal carotid pressure

Outcome

Cardiac output measured by a radioactive indicator dilution methodsurrogate

Lowering carotid pulse pressure in cats does not increase cardiac output, but rather leaves it unchanged or decreases it due to vagal inhibition.

Cite This Study

Groom et al. (1962) studied this question.

synapsesocial.com/papers/6a897b2cb1e5d05ea8ec737b https://doi.org/10.1111/j.1748-1716.1962.tb02336.x

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The Effect of Lowering the Pulse Pressure in the Carotid Arteries on the Cardiac Output in the Cat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Effect of Lowering the Pulse Pressure in the Carotid Arteries on the Cardiac Output in the Cat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider