Why the study?
Does electrical stimulation of the right and left stellate ganglia alter coronary hemodynamics and cardiac surface electrocardiogram in open-chest anesthetized dogs?
Population
22 adult mongrel dogs (weight 10-25 kg), open-chest anesthetized
Comparison
Electrical stimulation of unilateral right and… vs Baseline measurements before stimulation and…
Design
Preclinical
Follow-up
Up to 3 minutes post-stimulation
Authors
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Requires human validation before clinical use; leaves open beta-adrenergic roles in sympathetic cardiac control.
Does electrical stimulation of the right and left stellate ganglia alter coronary hemodynamics and cardiac surface electrocardiogram in open-chest anesthetized dogs?
Stellate ganglion stimulation alters coronary hemodynamics and local repolarization via beta-adrenergic receptor activation, with functional differences observed between right and left innervation.
Nobuhiko Yoshioka (1980) studied this question.
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