Population
Rabbit reticulocyte lysate, NIH-3T3 cells, and COS-7 cells
Design
Preclinical
Authors
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Leaves open clinical translation for lentiviral gene therapy; extends mechanistic insights into SIV translation in animal models.
The identification of an IRES in SIV provides insights into lentivirus replication and potential design of novel lentiviral vectors for gene transfer.
Ohlmann et al. (2000) studied this question.
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