What does this research mean for the field?

Plant-derived nanovesicles (PDNVs) represent a promising, biologically active, and sustainable alternative to conventional vesicular nanocarriers for controlled topical drug delivery in dermatology and cosmetology. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the isolation, characterization, and therapeutic potential of plant-derived nanovesicles as topical drug delivery systems in dermatology and cosmetology.

August 22, 2026ViewOpen Access

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

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Authors

DFDorotea Fiore BPBeatrice Pellegrini AMAntonia Mancuso

Discussion

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Overview

Narrative review demonstrates the therapeutic potential of plant-derived nanovesicles for topical drug delivery across the skin barrier, suggesting a sustainable alternative to synthetic carriers.

Key Points

To evaluate the isolation, characterization, and therapeutic potential of plant-derived nanovesicles as topical drug delivery systems in dermatology and cosmetology.
Reviewed literature on botanical sources, isolation, purification, characterization, and storage parameters affecting plant-derived nanovesicle yield and purity.
Compared plant-derived nanovesicles with conventional synthetic vesicular nanocarriers in terms of skin barrier interaction, safety profiles, industrial scalability, and regulatory barriers.
Identified that lipid-bilayer nanovesicles from plants efficiently traverse the stratum corneum while transporting bioactive proteins, lipids, and nucleic acids.
Summarized preclinical evidence confirming that plant-derived nanovesicles offer enhanced biocompatibility, intrinsic biological activity, and sustainability relative to conventional synthetic nanocarriers.

Cite This Study

Fiore et al. (2026) studied this question.

synapsesocial.com/papers/6a898131ca7ade938187f2f2 https://doi.org/10.1002/viw2.70194

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August 22, 2026ViewOpen Access

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

View Full Paper

Ask AI

Bookmark

Authors

DFDorotea Fiore BPBeatrice Pellegrini AMAntonia Mancuso

Discussion

Member takes

Overview

Narrative review demonstrates the therapeutic potential of plant-derived nanovesicles for topical drug delivery across the skin barrier, suggesting a sustainable alternative to synthetic carriers.

Key Points

To evaluate the isolation, characterization, and therapeutic potential of plant-derived nanovesicles as topical drug delivery systems in dermatology and cosmetology.
Reviewed literature on botanical sources, isolation, purification, characterization, and storage parameters affecting plant-derived nanovesicle yield and purity.
Compared plant-derived nanovesicles with conventional synthetic vesicular nanocarriers in terms of skin barrier interaction, safety profiles, industrial scalability, and regulatory barriers.
Identified that lipid-bilayer nanovesicles from plants efficiently traverse the stratum corneum while transporting bioactive proteins, lipids, and nucleic acids.
Summarized preclinical evidence confirming that plant-derived nanovesicles offer enhanced biocompatibility, intrinsic biological activity, and sustainability relative to conventional synthetic nanocarriers.

Cite This Study

Fiore et al. (2026) studied this question.

synapsesocial.com/papers/6a898131ca7ade938187f2f2 https://doi.org/10.1002/viw2.70194

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