"Penbritin": An Oral Penicillin with Broad-spectrum Activity

rPENBRITIN," A NEW PENICILLIN BDICJOURNAL Experiment 6.-For comparative purposes, 10 sub- jects received two 250-mg. capsules of tetracycline and a similar procedure was adopted as in the previous experiments except that no half-hour specimen was taken. The results are set out in Table Serum TABLE VII.-Serum Concentrations and Urinary Excretion of Tetracycline After a Single 500-mg. Dose Sub-Dose Serum Concentration (pg. 'ml.) Urine ject mg. l h 2 h mg. in mg I hr. 2 hr. 4 hr. 6 hr. 6 hr.