Key result
Bicuspid aortic valve disease is associated with an inherited underlying disease of the aorta, with novel molecular mechanisms and surgical therapies proposed in the past decade.
Population
Patients with bicuspid aortic valve disease
Design
Review
Authors
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May support aortopathy evaluation in bicuspid aortic valve; leaves open validation of novel mechanisms and therapies.
This review summarizes recent insights into the pathophysiology and treatment of bicuspid aortic valve disease, emphasizing the potential for an inherited aortopathy.
Fedak et al. (2005) conducted a review in Bicuspid aortic valve disease. Bicuspid aortic valve disease is associated with an inherited underlying disease of the aorta, with novel molecular mechanisms and surgical therapies proposed in the past decade.
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