Key result
A lower ankle brachial pressure index was independently associated with a higher apathy scale score, but not with a higher depression score, in a community-dwelling population.
Why the study?
Is a lower ankle brachial pressure index associated with apathy or depression in a community-dwelling population?
Cross-Sectional (n=860)
Is a lower ankle brachial pressure index associated with apathy or depression in a community-dwelling population?
A lower ankle brachial pressure index is associated with apathy, but not depression, suggesting different vascular etiologies for these neuropsychiatric syndromes.
Does not support ABI screening for apathy; hypothesis-generating for distinct vascular pathways versus depression.
BACKGROUND: Apathy is defined as a lack of interest or emotion. Several studies have shown the relationship between apathy and atherosclerotic change in poststroke patients. Although apathy is confused with depression, it might be a specific neuropsychiatric syndrome separate from depression. OBJECTIVE: To clarify the relationship between atherosclerotic change and apathy in a community-dwelling population, which does not include the psychologic factors associated with stroke events. METHODS: The ankle brachial pressure index (ABI) was measured using a volume-plethymographic apparatus in 860 volunteers (315 males and 545 females) who participated in the Iwaki Health Promotion Project 2008. Starkstein's apathy score and the Center for Epidemiologic Studies Depression Scale (CES-D) were used to assess the psychologic status. The association between the ABI and apathy was assessed by a multiple linear regression analysis. RESULTS: Gender and low-density lipoprotein (LDL)-cholesterol were independently and significantly associated with the CES-D score. We did not find any association between CES-D score and the ABI. In addition, the extent of education and the ABI were independently and significantly associated with the apathy scale (AS). CONCLUSION: In a community-dwelling population, a lower ABI score was an independent risk factor for a higher AS score, but not for a higher CES-D score. Apathy and depression may have different etiologies in vascular factors.
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Sugawara et al. (2010) conducted a cross-sectional in Apathy (n=860). Ankle brachial pressure index (ABI) was evaluated on Apathy scale (AS) score and Center for Epidemiologic Studies Depression Scale (CES-D) score. A lower ankle brachial pressure index was independently associated with a higher apathy scale score, but not with a higher depression score, in a community-dwelling population.
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