Key result
In 287 elderly subjects free of apathy and depression at baseline, each additional cardiovascular pathology was associated with a significantly higher increase in apathy over 5 years.
Why the study?
Does baseline vascular disease increase the risk of developing apathy in community-dwelling subjects aged 85 years and older?
Population
500 community-dwelling elderly subjects aged 85 years and older from the prospective, population-based…
Comparison
Presence of baseline vascular disease. vs Absence of or fewer baseline cardiovascular…
Design
Cohort
Follow-up
5 years (from age 85 through 90 years)
Authors
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May warrant apathy monitoring in vascular-burdened elders ≥85; leaves open causality and prevention trials.
Cohort (n=500)
Does baseline vascular disease increase the risk of developing apathy in community-dwelling subjects aged 85 years and older?
In community-dwelling elderly aged 85 and older, the presence of vascular disease is associated with a higher risk of developing apathy, suggesting a distinct vascular etiology for apathy separate from depression.
Mast et al. (2007) conducted a cohort in Apathy and vascular disease (n=500). Vascular disease vs. Absence of or fewer cardiovascular pathologies was evaluated on Development or increase of apathy. In 287 elderly subjects free of apathy and depression at baseline, each additional cardiovascular pathology was associated with a significantly higher increase in apathy over 5 years.
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