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Parenteral therapy remains the most reliable method of treating perniclous anaemia, but should this be contra- indicated then generous daily doses of either crystalline vitamin B,2 or vitamin-B12-peptide are as effective as any other form of oral therapy yet developed.I thank the physicians who referred cases to me for these trials; the patients for their co-operation; Dr. J. A. H. Waterhouse for help with the statistical analysis; Dr. J. N. Marshall Chalmers for his co-operation and advice; Mr. C. I. D. Wilson for technical assistance; and Distillers Co.(Biochemicals) Ltd. for supplying the vitamin-B12-peptide.
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Dormandy et al. (1961) studied this question.
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