Key result
Increased fetal modified myocardial performance index was significantly associated with adverse perinatal outcomes in both early-onset (OR 3.307) and late-onset (OR 3.412) fetal growth restriction.
Why the study?
The study aimed to investigate changes in modified myocardial performance index in early-onset and late-onset fetal growth restriction and its association with adverse perinatal outcome.
Does the modified myocardial performance index (Mod-MPI) predict adverse perinatal outcomes in fetuses with early-onset and late-onset fetal growth restriction?
Cohort (n=377)
No
Does the modified myocardial performance index (Mod-MPI) predict adverse perinatal outcomes in fetuses with early-onset and late-onset fetal growth restriction?
Odds Ratio: 3.307 (95% CI 1.425–7.674)
p-value: p=0.005
The modified myocardial performance index (Mod-MPI) is an effective echocardiographic parameter that supplements standard Doppler imaging for predicting adverse perinatal outcomes in fetal growth restriction.
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Mod-MPI may aid perinatal risk stratification in FGR; observational data leave open incremental value over standard Doppler.
Zhang et al. (2019) conducted a cohort in Fetal growth restriction (n=377). Fetal modified myocardial performance index (Mod-MPI) vs. Normal fetuses was evaluated on Adverse perinatal outcome in early-onset fetal growth restriction (OR 3.307, 95% CI 1.425-7.674, p=0.005). Increased fetal modified myocardial performance index was significantly associated with adverse perinatal outcomes in both early-onset (OR 3.307) and late-onset (OR 3.412) fetal growth restriction.
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