What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Singleton pregnancies (n=202). Intervention: Fetal echocardiography. Primary outcome: Fetal cardiocirculatory dynamics reference values (heart:chest area ratio, Tei index, outflow velocities).

What question did this study set out to answer?

To evaluate fetal cardiocirculatory dynamics during first-trimester screening and establish normal cross-sectional reference ranges for 11–14 weeks of gestation.

February 22, 2010Ultrasound in Obstetrics and GynecologyOpen Access

Reference values for variables of fetal cardiocirculatory dynamics at 11–14 weeks of gestation

View Full Paper

Ask AI

Bookmark

Key result

Fetal echocardiography at 11-14 weeks' gestation established reference ranges for cardiocirculatory dynamics, showing the mean Tei index of the LV (0.375) was higher than the RV (0.332; P=0.001).

Population

202 women with singleton pregnancies at 11 + 0 to 13 + 6 weeks' gestation

Design

Cross-sectional

Follow-up

until birth (to confirm normality)

Authors

WRWioletta Rozmus-WarcholińskaMedical University of Silesia AWAgata WłochMedical University of Silesia GAGanesh AcharyaKarolinska University Hospital

Discussion

Member takes

Implication

Offers early fetal cardiac reference values; hypothesis-generating until validated against outcomes.

Key Points

To evaluate fetal cardiocirculatory dynamics during first-trimester screening and establish normal cross-sectional reference ranges for 11–14 weeks of gestation.
Conducted fetal echocardiography in 202 women with singleton pregnancies between 11 + 0 and 13 + 6 weeks of gestation.
Assessed global, systolic, and diastolic cardiac function using heart : chest area ratio, left and right ventricular Tei indices, cardiac cycle phase durations, ventricular outflow velocities, E:A ratios, and ductus venosus pulsatility index for veins (DV-PIV).
Confirmed normal cardiac development via follow-up fetal echocardiography in the second trimester and post-birth neonatal examination.
The mean heart : chest area ratio was 0.203 ± 0.04 and mean DV-PIV was 0.97 ± 0.23, with neither varying significantly over weeks 11–14 (P = 0.95 for DV-PIV).
Mean left ventricular Tei index was significantly higher than the right ventricle (0.375 ± 0.092 vs 0.332 ± 0.079; P = 0.001), while fetal heart rate decreased with increasing crown-rump length (P < 0.00001).
Left (P = 0.004) and right (P < 0.00001) ventricular outflow velocities, along with biventricular E:A ratios (P < 0.0001), increased significantly across gestational age.

Study Design

Type

Cross-Sectional (n=202)

Structured PICO

Population

202 women with singleton pregnancies at 11 to 14 weeks' gestation undergoing fetal echocardiography to establish reference ranges for fetal cardiocirculatory dynamics.

Exposure

Fetal echocardiography during routine first-trimester screening

Outcome

Cross-sectional reference ranges for fetal cardiocirculatory dynamics (heart:chest area ratio, Tei index, ICT%, ET%, IRT%, FT%, outflow velocities, E:A ratio, DV-PIV)surrogate

This study establishes normal reference ranges for fetal echocardiographic parameters at 11-14 weeks' gestation, aiding in the early evaluation of fetal heart function.

Cite This Study

Rozmus-Warcholińska et al. (2010) conducted a cross-sectional in Singleton pregnancies (n=202). Fetal echocardiography was evaluated on Fetal cardiocirculatory dynamics reference values (heart:chest area ratio, Tei index, outflow velocities). Fetal echocardiography at 11-14 weeks' gestation established reference ranges for cardiocirculatory dynamics, showing the mean Tei index of the LV (0.375) was higher than the RV (0.332; P=0.001).

synapsesocial.com/papers/6a89b484a90c2f4c44fba31c https://doi.org/10.1002/uog.7595

View Full Paper

Ask AI

Bookmark

Reference values for variables of fetal cardiocirculatory dynamics at 11–14 weeks of gestation

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Reference values for variables of fetal cardiocirculatory dynamics at 11–14 weeks of gestation

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider