Population
Fragmented sarcoplasmic reticulum (FSR)
Design
Preclinical
Authors
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Animal data on FSR Ca release remain preliminary; leaves open relevance to human cardiac Ca handling or therapy.
The study demonstrates that AMPOPCP induces Ca release from fragmented sarcoplasmic reticulum, suggesting the FSR-ATP complex state is crucial for Ca-induced Ca release.
Ogawa et al. (1976) studied this question.
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