Why the study?
Does intraduodenal glucose infusion affect blood pressure, heart rate, and noradrenaline responses differently in obese versus healthy subjects?
Population
35 subjects, comprising 12 obese subjects and 23 healthy controls
Comparison
Intraduodenal infusion of glucose at 1 or 3… vs Intraduodenal saline infusion for 60 minutes
Design
Other
Follow-up
120 minutes
Authors
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Comparable responses to controlled glucose delivery in obese and non-obese subjects; hypothesis-generating for gastric emptying's role in postprandial changes.
Does intraduodenal glucose infusion affect blood pressure, heart rate, and noradrenaline responses differently in obese versus healthy subjects?
Cardiovascular and sympathetic responses to intraduodenal glucose are dependent on the rate of glucose delivery but are comparable between obese and healthy subjects when gastric emptying is bypassed.
Trahair et al. (2018) studied this question.
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