Why the study?
Does the rate of intraduodenal glucose delivery influence the magnitude of postprandial blood pressure fall in healthy older subjects?
Population
8 healthy elderly subjects, mean age 70.3 +/- 3.4 years, 50% male
Comparison
Intraduodenal glucose infusion at a rate of 3… vs Intraduodenal glucose infusion at a rate of 1…
Design
RCT, randomised order, double-blind
Follow-up
120 minutes
Authors
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Slower intraduodenal glucose delivery may attenuate postprandial hypotension in older adults; confirms rate-dependent cardiovascular effects of nutrient delivery.
Does the rate of intraduodenal glucose delivery influence the magnitude of postprandial blood pressure fall in healthy older subjects?
In healthy older subjects, the magnitude of postprandial blood pressure fall and heart rate increase is dependent on the rate of nutrient delivery into the small intestine.
O’Donovan et al. (2002) studied this question.
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