Key result
Adding guar gum to an intraduodenal glucose infusion significantly attenuated the fall in systolic blood pressure (P=0.03) and increase in heart rate (P=0.027) in healthy older adults.
Why the study?
Does intraduodenal guar gum reduce the fall in blood pressure induced by intraduodenal glucose in healthy older adults?
RCT (n=8)
Single-blind
randomized
Does intraduodenal guar gum reduce the fall in blood pressure induced by intraduodenal glucose in healthy older adults?
p-value: p=0.03
Adding guar gum to intraduodenal glucose attenuates the postprandial fall in systolic blood pressure and rise in heart rate in healthy older adults.
No takes yet. Share an insight, caveat, or question.
May support oral guar gum trials for postprandial hypotension; extends RCT evidence on viscosity modulating postprandial hemodynamics in older adults.
O’Donovan et al. (2005) conducted an RCT in Healthy (n=8). Guar gum added to intraduodenal glucose infusion vs. Intraduodenal glucose infusion without guar gum was evaluated on Magnitude of the fall in systolic blood pressure between t = 0 and t = 30 minutes (p=0.03). Adding guar gum to an intraduodenal glucose infusion significantly attenuated the fall in systolic blood pressure (P=0.03) and increase in heart rate (P=0.027) in healthy older adults.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: