Population
22 patients with idiopathic dilated cardiomyopathy and 20 with ischemic cardiomyopathy who underwent cardiac…
Design
Cross-sectional
Authors
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Suggests disease-specific ET activation in ICM; hypothesis-generating for targeted therapies pending prospective validation.
The cardiac endothelin-1 system is selectively upregulated in patients with ischemic cardiomyopathy compared to idiopathic dilated cardiomyopathy, suggesting a functional role in maintaining cardiac function in ICM.
Serneri et al. (2000) studied this question.
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