Why the study?
Does antenatal diagnosis of major congenital heart disease correlate with different patient characteristics and outcomes compared to postnatal diagnosis?
Population
272 patients with major congenital heart disease in Northern Ireland between January 1, 2002 and December…
Comparison
Antenatal diagnosis vs Postnatal or post-mortem diagnosis
Design
Cohort
Follow-up
up to 28 days postnatally
Authors
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Antenatal detection may flag higher-risk CHD for specialized counseling; leaves open screening impact on population outcomes in cohorts.
Does antenatal diagnosis of major congenital heart disease correlate with different patient characteristics and outcomes compared to postnatal diagnosis?
Antenatal detection of major CHD identifies a subset of patients with more complex defects, higher rates of chromosomal abnormalities, and poorer neonatal outcomes compared to those diagnosed postnatally.
McBrien et al. (2008) studied this question.
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