Population
Isolated papillary muscles of guinea-pigs
Design
Preclinical
Authors
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Preclinical cardiac glycoside data should not alter practice; hypothesis-generating for distinct myocardial mechanisms.
The differential rates of change in contractile force and action potential duration induced by cardiac glycosides suggest the involvement of multiple sites of action in cardiac muscle.
Lüllmann et al. (1973) studied this question.
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