Population
61 patients with no evidence of infectious or demyelinating disease of the central nervous system
Design
Cross-sectional
Authors
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CSF antibody ratios require total IgG normalization; leaves open diagnostic utility pending prospective validation.
The distribution of antiviral IgG antibodies in serum and CSF normally follows the distribution of total IgG, suggesting the IgG ratio should be used in evaluating disturbed antibody ratios.
Kalimo et al. (1977) studied this question.
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