This case report describes a rare presentation of primary thyroid angiosarcoma treated with surgery and radiotherapy.
May inform management of rare thyroid angiosarcoma with surgery plus radiotherapy; leaves open long-term outcomes and optimal protocols.
The authors described a case of rare histological type of primary thyroid tumour: angiosarcoma. We report a case of 37 years old female who presented with the mass in the anterior of the neck that had been rapidly growing for several months. Scintigraphy showed a cold nodule in the left lobe of the thyroid. The patient underwent subtotal thyroidectomy. The cut surface showed a bulging solid grey hemorrhagic mass, measuring 6.5 cm at the lower pole of the left lobe. Microscopically a poorly differentiated highly desmoplastic polymorphocellular tumour. Immunohistochemically, the cells showed immunoreactivity for endothelial markers CD31, CD34, Facor VIII related antigen and immunonegativity for epithelial markers including pancytokeratin, epithelial membrane antigen and thyroglobulin. Radiotherapy was applied. The patient was alive after a follow up of five months. doi:10.4021/jmc2010.07.107e
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