November 30, 1990Science

A Borna Virus cDNA Encoding a Protein Recognized by Antibodies in Humans with Behavioral Diseases

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Population

BDV-infected MDCK cell line, BDV-infected rat brain tissue, and sera from patients with behavioral disorders

Design

Preclinical

Authors

JRJüergen A. RichtKansas State University MZM. Christine ZinkJohns Hopkins University RRR. RottUnited States Department of Health and Human Services

Discussion

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Implication

Supports BDV molecular studies in behavioral disorders; leaves open any pathogenic role or clinical relevance.

Structured PICO

Population

BDV-infected MDCK cell line, BDV-infected rat brain tissue, and sera from patients with behavioral disorders (n=7)

Intervention

Construction of a subtractive complementary DNA expression library and isolation of clone B8

Outcome

Identification of BDV genome and synthesis of BDV-specific proteinssurrogate

The identification of a BDV-specific cDNA clone provides a means to isolate other BDV nucleic acids and investigate its potential role as a human pathogen in behavioral disorders.

Cite This Study

Richt et al. (1990) studied this question.

synapsesocial.com/papers/6a89c998176d2ac34cfbb7f7 https://doi.org/10.1126/science.2244211

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A Borna Virus cDNA Encoding a Protein Recognized by Antibodies in Humans with Behavioral Diseases

Discussion

Member takes

Implication

Structured PICO

Cite This Study

A Borna Virus cDNA Encoding a Protein Recognized by Antibodies in Humans with Behavioral Diseases

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider