Isolation and characterization of Borna disease agent cDNA clones.
Population
Rat with Borna disease (BD)
Design
Preclinical
Authors
Discussion
Loading...
Member takes
Implication
Supports BD viral characterization in rat models; leaves open human translation and clinical relevance pending validation.
Structured PICO
P
Population
Rat with Borna disease (BD)
I
Intervention
Isolation and characterization of cDNA clones
O
Outcome
Identification of specific transcripts in BD rat brain and characterization of the BD agent
The isolation of cDNA clones from a rat with Borna disease provides evidence that the etiologic agent is likely a virus with specific major transcripts.
Cite This Study
Lipkin et al. (1990) studied this question.