Why the study?
Does des-aspartyl1-angiotensin II compared to angiotensin II differentially affect blood pressure and aldosterone production in patients with essential hypertension?
Population
21 patients with essential hypertension
Comparison
Constant infusion of des-aspartyl1-angiotensin… vs Constant infusion of angiotensin II for 45 min…
Design
Other
Follow-up
45 min
Authors
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May implicate des-aspartyl1-angiotensin II in aldosterone excess in hypertension; leaves open its differential role versus angiotensin II.
Does des-aspartyl1-angiotensin II compared to angiotensin II differentially affect blood pressure and aldosterone production in patients with essential hypertension?
Des-aspartyl1-angiotensin II appears to play a more important role than angiotensin II in aldosterone production in essential hypertension.
Mizuno et al. (1980) studied this question.
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