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August 4, 2020Clinical Kidney JournalOpen Access

Acute kidney injury may impede results after transcatheter aortic valve implantation

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Why the study?

TAVI-related haemodynamic instability and infection risk may impair renal functional reserve, but the incidence, modifiable risk factors, and prognosis of AKI and complicated AKI after TAVI required investigation.

What is the incidence, risk factors, and prognostic impact of acute kidney injury after transcatheter aortic valve implantation?

Population

804 consecutive patients hospitalized for elective TAVI

Comparison

Patients with AKI vs without AKI after TAVI

Design

Retrospective single-centre study

Follow-up

Up to 6 months after index-hospitalization

Authors

AHAnja Haase‐FielitzMedizinische Hochschule Brandenburg Theodor FontaneFAFiona AltendeiteringMedizinische Hochschule Brandenburg Theodor FontaneRIRagna IwersOtto-von-Guericke University Magdeburg

Discussion

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Implication

AKI after TAVI signals high in-hospital mortality risk warranting close monitoring; leaves open whether prevention reduces death in observational data.

Structured PICO

What is the incidence, risk factors, and prognostic impact of acute kidney injury after transcatheter aortic valve implantation?

P
Population
804 consecutive patients hospitalized during 2017 and 2018 for elective transcatheter aortic valve implantation (TAVI)
I
Intervention
Transcatheter aortic valve implantation (TAVI)
O
Outcome
Incidence, modifiable risk factors, and prognosis of acute kidney injury (AKI) and in-hospital mortalityhard clinical

Acute kidney injury is a common complication after TAVI (13.8%) and is strongly associated with increased in-hospital mortality, highlighting the need for careful renal monitoring and management.

Cite This Study

Haase‐Fielitz et al. (2020) studied this question.

synapsesocial.com/papers/6a8a40f7f8670bac6e336a85https://doi.org/10.1093/ckj/sfaa179
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence, risk factors and prognosis of acute kidney injury after transcatheter aortic valve implantation2012 · 62 citations
  2. 2Risk factors for worsening renal function and their association with long-term mortality following transcatheter aortic valve implantation: data from the SWEDEHEART registry2017 · 13 citations
  3. 3Acute kidney injury after transcatheter aortic valve implantation with self-expanding CoreValve prosthesis: results from a large multicentre Italian research project2014 · 64 citations
  4. 42017 ESC/EACTS Guidelines for the management of valvular heart disease2017 · 6,338 citations
  5. 5Distant organ dysfunction in acute kidney injury2019 · 47 citations