May 1, 2014EuroIntervention
Acute kidney injury after transcatheter aortic valve implantation with self-expanding CoreValve prosthesis: results from a large multicentre Italian research project
Why the study?
Does post-procedural acute kidney injury increase mortality in patients with severe aortic stenosis undergoing TAVI?
Population
n=1,157 patients with severe aortic stenosis treated with the third-generation CoreValve prosthesis in seven…
Comparison
Post-procedural acute kidney injury after TAVI vs No post-procedural AKI
Design
Cohort
Follow-up
3 years
Authors
Discussion
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Member takes
Implication
Post-TAVI AKI warrants close monitoring; leaves open whether prevention reduces mortality in prospective trials.
Structured PICO
Does post-procedural acute kidney injury increase mortality in patients with severe aortic stenosis undergoing TAVI?
P
Population
n=1,157 patients with severe aortic stenosis treated with the third-generation CoreValve prosthesis in seven Italian sites, with creatinine data available at baseline and during the post-TAVI in-hospital course.
I
Intervention
Post-procedural acute kidney injury (AKI) after TAVI
C
Comparator
No post-procedural AKI
O
Outcome
Three-year all-cause mortality and cardiovascular mortalityhard clinical
Post-procedural acute kidney injury after TAVI is a frequent complication (20%) that independently doubles the risk of three-year all-cause and cardiovascular mortality.
Cite This Study
Barbanti et al. (2014) studied this question.