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January 1, 2012SHILAP Revista de lepidopterologíaOpen Access

The Risk of Acute Kidney Injury and Its Impact on 30-Day and Long-Term Mortality after Transcatheter Aortic Valve Implantation

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Why the study?

Does the development of acute kidney injury after transcatheter aortic valve implantation increase 30-day and long-term mortality in high-risk patients with aortic stenosis?

Population

140 high-risk patients with aortic stenosis undergoing transcatheter aortic valve implantation, mean age 81…

Comparison

Development of acute kidney injury post-TAVI vs No acute kidney injury post-TAVI

Design

Cohort

Follow-up

30-day and long-term

Authors

KGKatrin GebauerÇevre ve Şehircilik BakanlığıGDGerhard‐Paul DillerAdult Congenital Heart DiseaseGKGerrit KaleschkeKlinik und Poliklinik für Psychosomatik und Psychotherapie

Discussion

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Implication

Post-TAVI AKI was associated with higher mortality; hypothesis-generating for prevention trials before practice change.

Structured PICO

Does the development of acute kidney injury after transcatheter aortic valve implantation increase 30-day and long-term mortality in high-risk patients with aortic stenosis?

P
Population
140 high-risk patients with aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) (150 consecutive patients initially, 10 excluded due to chronic hemodialysis), mean age 81 ± 7 years, logistic EuroSCORE 24 ± 15%.
I
Intervention
Development of acute kidney injury (creatinine rise ≥26.5 μmol/L within 48 hours) post-TAVI
C
Comparator
No acute kidney injury post-TAVI
O
Outcome
30-day mortality and long-term mortalityhard clinical

Post-procedural acute kidney injury is a frequent complication (20%) after TAVI and is associated with significantly increased 30-day and long-term mortality.

Cite This Study

Gebauer et al. (2012) studied this question.

synapsesocial.com/papers/69d570a575589c71d767ddfehttps://doi.org/10.1155/2012/483748
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence, risk factors and prognosis of acute kidney injury after transcatheter aortic valve implantation2012 · 62 citations
  2. 2Risk of acute kidney injury in patients with severe aortic valve stenosis undergoing transcatheter valve replacement2009 · 191 citations
  3. 3Frequency, determinants, and prognostic effects of acute kidney injury and red blood cell transfusion in patients undergoing transcatheter aortic valve implantation2010 · 148 citations
  4. 4Morbidity, mortality and economic burden of renal impairment in cardiac intensive care2006 · 23 citations
  5. 5Acute Kidney Injury After Cardiac Surgery2009 · 741 citations