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July 6, 2022Rational Pharmacotherapy in CardiologyOpen Access

Acute Kidney Injury after Transcatheter Aortic Valve Implantation

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Key result

High hs-cTnI level was a significant predictor of acute kidney injury after TAVI (OR 4.0; 95% CI 1.0-16.1), which occurred in 12% of patients and was associated with increased hospital complications.

Why the study?

The study aimed to evaluate the incidence and predictors of acute kidney injury associated with transcatheter aortic valve implantation.

What is the incidence and what are the predictors of acute kidney injury after transcatheter aortic valve implantation?

Population

50 patients aged 76 (71; 80) years who underwent TAVI

Comparison

Patients with AKI vs patients without AKI after TAVI

Design

Observational study

Follow-up

Hospital stay

Authors

ЛКЛ. В. КремневаTyumen State Medical UniversityСШС. В. ШалаевClinical Hospital No. 8DKD. V. KrashenininClinical Hospital No. 8

Discussion

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Implication

May flag high hs-cTnI patients for closer post-TAVI AKI surveillance; hypothesis-generating and requires prospective validation.

Study Design

Type

Observational (n=50)

Structured PICO

What is the incidence and what are the predictors of acute kidney injury after transcatheter aortic valve implantation?

P
Population
50 patients (78% female, mean age 76 years) undergoing transcatheter aortic valve implantation, evaluated for the incidence and predictors of acute kidney injury during the hospital stay.
E
Exposure
Transcatheter aortic valve implantation (TAVI)
O
Outcome
Incidence and predictors of acute kidney injury (AKI) diagnosed according to KDIGO criteria (2012)safety

Main Result

Odds Ratio: 4 (95% CI 1–16.1)

p-value: p=0.013

Acute kidney injury occurs in 12% of patients following TAVI, is predicted by elevated hs-cTnI levels, and is associated with significantly worse in-hospital outcomes.

Cite This Study

Кремнева et al. (2022) conducted an observational in Transcatheter aortic valve implantation (TAVI) (n=50). High hs-cTnI level vs. Lower hs-cTnI level was evaluated on Acute kidney injury (AKI) (OR 4.0, 95% CI 1.0-16.1, p=0.013). High hs-cTnI level was a significant predictor of acute kidney injury after TAVI (OR 4.0; 95% CI 1.0-16.1), which occurred in 12% of patients and was associated with increased hospital complications.

synapsesocial.com/papers/6a7da9e2f9fad9e96bb86fc8https://doi.org/10.20996/1819-6446-2022-06-10
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute kidney injury after transcatheter aortic valve implantation and mortality risk—long-term follow-up2018 · 32 citations
  2. 2Acute kidney injury may impede results after transcatheter aortic valve implantation2020 · 15 citations
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