What question did this study set out to answer?

To evaluate whether the hemoglobin-albumin-lymphocyte-platelet (HALP) score can serve as an accessible prognostic marker in patients diagnosed with idiopathic pulmonary fibrosis.

July 21, 2025CureusOpen Access

Can the Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) Index Be Used as a Prognostic Marker in Patients Diagnosed With Idiopathic Pulmonary Fibrosis?

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Authors

EAEsma Sevil AkkurtUniversity of Health Science KEKerem EnsarıoğluUniversity of Health Science BÖBerna Akıncı ÖzyürekUniversity of Health Science

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Implication

Cohort study reveals that a higher HALP score predicts longer survival in idiopathic pulmonary fibrosis, indicating its value as a simple prognostic biomarker.

Key Points

To evaluate whether the hemoglobin-albumin-lymphocyte-platelet (HALP) score can serve as an accessible prognostic marker in patients diagnosed with idiopathic pulmonary fibrosis.
Retrospective cohort analysis of 224 patients diagnosed with idiopathic pulmonary fibrosis followed at a tertiary pulmonary clinic between January 2021 and March 2023.
Recorded clinical characteristics, comorbidities, laboratory indices, pulmonary function tests with carbon monoxide diffusing capacity (PFT-DLCO), six-minute walk test results, and survival outcomes.
A HALP score cutoff of 25 stratified survival duration, with patients scoring >25 achieving a median survival of 981 days (range: 752–1209) compared to 493 days (range: 40–945) for those scoring ≤25 (log-rank test P=0.01, χ²(1)=6.693).
The study population had a mean age of 66.27 ± 8.83 years, was predominantly male (84%), and presented with an overall mean HALP score of 53.27 ± 27.73.

Cite This Study

Akkurt et al. (2025) studied this question.

synapsesocial.com/papers/6a8a4d8b754a5a619a7231af https://doi.org/10.7759/cureus.88423

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Implication

Cohort study reveals that a higher HALP score predicts longer survival in idiopathic pulmonary fibrosis, indicating its value as a simple prognostic biomarker.

Can the Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) Index Be Used as a Prognostic Marker in Patients Diagnosed With Idiopathic Pulmonary Fibrosis?

Discussion

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Implication

Key Points

Cite This Study

Can the Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) Index Be Used as a Prognostic Marker in Patients Diagnosed With Idiopathic Pulmonary Fibrosis?

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Implication

Key Points

Cite This Study

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