Why the study?
Does continuous positive and negative pressure breathing alter hemodynamics in normal young men?
Population
36 normal young men
Design
Other
Authors
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May inform ventilation strategies favoring negative pressure; leaves open validation in patients with cardiovascular disease.
Does continuous positive and negative pressure breathing alter hemodynamics in normal young men?
Decreased intrathoracic pressure (negative pressure breathing) increases cardiac output and central blood volume, highlighting its role in maintaining blood availability to the heart.
Kilburn et al. (1960) studied this question.
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