September 1, 1996Circulation
Response of Type I Atrial Fibrillation to Atrial Pacing in Humans
Why the study?
Does high right atrial pacing during type I atrial fibrillation capture local tissue and influence left atrial electrograms in humans?
Population
24 patients with type I atrial fibrillation undergoing study in the electrophysiology laboratory
Comparison
Pacing at the high right atrium during type I AF… vs Baseline tachycardia and pacing that did not…
Design
Other
Authors
Discussion
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Member takes
Implication
Supports excitable gap in type I AF; hypothesis-generating for pacing-based termination before clinical trials.
Structured PICO
Does high right atrial pacing during type I atrial fibrillation capture local tissue and influence left atrial electrograms in humans?
P
Population
24 patients with type I atrial fibrillation undergoing study in the electrophysiology laboratory
I
Intervention
Pacing at the high right atrium during type I AF at cycle lengths 10, 20, 30, 40, and 50 ms less than the mean baseline atrial cycle length
C
Comparator
Baseline tachycardia (before pacing) and pacing that did not result in local capture
O
Outcome
Local capture of the right atrium and left atrial electrogram densitysurrogate
High right atrial pacing during type I atrial fibrillation can capture local tissue and influence left atrial electrograms, confirming the presence of an excitable gap.
Cite This Study
Daoud et al. (1996) studied this question.