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October 18, 2007Acta Anaesthesiologica ScandinavicaOpen Access

Changes in heart rate variability may reflect sympatholysis during spinal anaesthesia

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Why the study?

Do baseline heart rate variability parameters predict autonomic and hemodynamic changes during spinal anaesthesia in pregnant women?

Population

100 pregnant women scheduled for elective Caesarean section

Comparison

Spinal anaesthesia vs Patients stratified by baseline LF/HF ratio

Design

Cohort

Follow-up

15 minutes after spinal anaesthesia

Authors

RHR. HanßHOHenning OhnesorgeMKMark Kaufmann

Discussion

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Overview

Baseline LF/HF >2.5 was associated with more severe hypotension; leaves open whether HRV monitoring should guide obstetric anesthesia.

Structured PICO

Do baseline heart rate variability parameters predict autonomic and hemodynamic changes during spinal anaesthesia in pregnant women?

P
Population
100 pregnant women scheduled for elective Caesarean section
I
Intervention
Spinal anaesthesia
C
Comparator
Patients stratified by baseline LF/HF ratio (Group LF/HF < 2.5 [n=52] vs. Group LF/HF > 2.5 [n=48])
O
Outcome
Changes in systolic blood pressure (SBP) and heart rate variability (LF/HF, LF, HF) at 5 min and 15 min after spinal anaesthesiasurrogate

Changes in heart rate variability during spinal anaesthesia reflect sympatholysis and correlate with the severity of subsequent hypotension.

Cite This Study

Hanß et al. (2007) studied this question.

synapsesocial.com/papers/6a8a53614c30e1095aeca96chttps://doi.org/10.1111/j.1399-6576.2007.01455.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heart Rate Variability Predicts Severe Hypotension after Spinal Anesthesia2006 · 112 citations
  2. 2Heart Rate Variability Predicts Severe Hypotension after Spinal Anesthesia for Elective Cesarean Delivery2005 · 147 citations
  3. 3Analysis of Heart Rate Dynamics as a Measure of Autonomic Tone in Obstetrical Patients Undergoing Epidural or Spinal Anesthesia1994 · 23 citations
  4. 4Low-frequency Spectral Power of Heart Rate Variability Is Not a Specific Marker of Cardiac Sympathetic Modulation 1995 · 143 citations
  5. 5Heart Rate Variability–guided Prophylactic Treatment of Severe Hypotension after Subarachnoid Block for Elective Cesarean Delivery2006 · 94 citations